Penicillin doses may need to be increased as youngsters are getting heavier, The Daily Telegraph has reported. The newspaper said that dosing guidelines for penicillin and related antibiotics have not changed for almost 50 years, and are mostly based on children's ages rather than their weight.
This story is based on a review that examined how recommended doses of penicillin drugs have changed over the last 60 years. The review said that adult guidelines have been revised several times but that children’s penicillin guidelines have not been updated since the late 1950s. This means that doses are too low for today’s children. Currently, the British National Formulary for Children recommends different doses of penicillins depending on the individual drug and the condition being treated. For example, sometimes a dose recommendation is given by weight (such as amoxicillin for the treatment of ear infection), but in other cases the dose may be decided using age ranges (such as amoxicillin for the treatment of urinary tract infection). Prescription guidelines may also vary slightly from the dosing information provided by the manufacturer.